Nogapendekin alfa has a low likelihood of approval for gastroesophageal junction carcinomas.

Nogapendekin alfa is under clinical development by and currently in Phase II for Gastroesophageal (GE) Junction Carcinomas. According to GlobalData, Phase II drugs for Gastroesophageal (GE) Junction Carcinomas have a 28% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. Smarter leaders trust GlobalData The gold standard of business intelligence. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Nogapendekin alfa overview nogapendekin alfa (ALT-803) is under development for the treatment of relapsed or refractory multiple myeloma, gastroesophageal (GE) junction carcinomas, metastatic castration resistant prostate cancer, hematological tumor such as acute lymphoblastic leukemia (ALL), myelodysplastic syndromes (MDS) lymphoma, chronic lymphocytic leukemia (CLL), small cell lung cancer, urothelial carcinoma, Merkle cell carcinoma, gastric cancer, cervical cancer, hepatocellular carcinoma, small lymphocytic lymphoma or lymphoplasmacytic lymphoma, chronic myelogenous leukemia (CML), hereditary nonpolyposis colon cancer, non-small cell lung cancer, squamous non-small cell lung carcinoma, renal cell carcinoma, squamous cell head and neck carcinoma, metastatic melanoma, pancreatic cancer, relapsed or refractory non-Hodgkin lymphoma, primary peritoneal cancer, ovarian cancer, fallopian tube cancer, recurrent glioblastoma multiforme, gliosarcoma and HIV infections, the relapse of hematologic malignancies after ASCT and coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ALT-803 is administered through parenteral, intravesical, intravenous, intraperitoneal and subcutaneous route. It acts by targeting IL2RG and IL2RB. It was under development for relapsed or refractory acute myelocytic leukemia. It was also under development for non-muscle invasive bladder cancer, B-cell non-Hodgkin lymphoma, follicular lymphoma, waldenstrom macroglobulinemia (lymphoplasmacytic lymphoma), marginal zone B-cell lymphoma. ImmunityBio overview , a subsidiary of NantWorks LLC, is a clinical-stage biotechnology company developing therapies for therapies for cancer and infectious diseases. The company product pipeline includes anktiva + BCG, anktiva + keytruda (pembrolizumab), aldox + anktiva + PD-L1 t-hank, anktiva + tri-ad5 vaccines, anktiva + bevacizumab + PD-L1 t-hank, anktiva + IBRX-042 vaccination, anktiva + M-ceNK and anktiva + CD19 t-haNK. pipeline candidates treat bladder cancer, lung cancer, lynch syndrome, pancreatic cancer, glioblastoma, HPV, advanced Solid tumors, non-hodgkin lymphoma and HIV. The company operates in Italy, South Korea and the US. is headquartered in San Diego, California, the US. For a complete picture of Nogapendekin alfa’s drug-specific PTSR and LoA scores, This content was updated on 23 December 2004 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s . Smarter leaders trust GlobalData The gold standard of business intelligence.

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